abstract：:Mastocytosis is a heterogeneous disease caused by excessive mast cell (MC) proliferation. Diagnosis of systemic mastocytosis (SM) is based on the presence of major and minor criteria defined by the World Health Organization. Symptoms of MC activation can also occur in patients without SM or without allergic or inflamm...

journal_title：Acta clinica Belgica

authors： Van den Poel B,Kochuyt AM,Del Biondo E,Dewaele B,Lierman E,Tousseyn T,de Hertogh G,Vandenberghe P,Boeckx N

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:The development of combination antiretroviral therapies (cART) represents a significant advance in the treatment of (human immunodeficiency virus) HIV infection. However, several studies report that a large percentage of individuals with HIV, particularly those receiving cART, present body composition differ...

journal_title：Acta clinica Belgica

authors： Chițu-Tișu CE,Barbu EC,Lazăr M,Bojincă M,Tudor AM,Hristea A,Abagiu AO,Ion DA,Bădărău AI

更新日期：2017-02-01 00:00:00

abstract：INTRODUCTION:In many health care systems, strategies are currently deployed to engage patients and other stakeholders in decisions affecting hospital services. In this paper, a model for stakeholder involvement is presented and evaluated in three Flemish hospitals. In the model, a stakeholder committee advises the hosp...

journal_title：Acta clinica Belgica

authors： Malfait S,Van Hecke A,Hellings J,De Bodt G,Eeckloo K

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Sarcoidosis is a multisystem inflammatory disorder of unknown etiology. It is characterized by the presence of noncaseating granulomas and an inflammatory process in which T lymphocytes, especially type-1 helper T (Th1) cells, macrophages and different cytokines are involved. Different studies ...

journal_title：Acta clinica Belgica

authors： Esendagli D,Koksal D,Emri S

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Yellow nail syndrome (YNS) is a rare disorder of unknown aetiology characterized by the triad of yellow nails, lymphoedema and respiratory manifestations. About 200 cases have been reported, but a lot of patients probably elude proper diagnosis because of both variability of symptoms and ignora...

journal_title：Acta clinica Belgica

authors： Gregoire C,Guiot J,Vertenoeil G,Willems É,Hafraoui K,Corhay JL,Louis R,Beguin Y

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:The aim of this pilot study was to evaluate long-term effects of Roux-en-Y gastric bypass (RYGB) on physical and psychosocial health as well as eating behavior of obese patients. METHODS:We compared 23 patients 7 years after RYGB to 23 body mass index (BMI), sex, and age matched obese control patients by me...

journal_title：Acta clinica Belgica

authors： Vangoitsenhoven R,Frederiks P,Gijbels B,Lannoo M,Van der Borght W,Van den Eynde A,Mertens A,Mathieu C,Van der Schueren B

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVES:Q fever is a global zoonosis that can cause both acute and chronic infections in humans through aerogenic transmission. Although Q fever was discovered already 80 years ago, this infectious disease remains largely unknown. We studied a case series in a Belgian tertiary care hospital. METHODS:A laboratory an...

journal_title：Acta clinica Belgica

authors： Vanderbeke L,Peetermans WE,Saegeman V,De Munter P

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVES:Some infections require prolonged parenteral antimicrobial therapy, which can be continued in an outpatient setting. The Ghent University Hospital has 15 years of experience with Outpatient Parenteral Antimicrobial Therapy (OPAT) in the home setting of the patient. METHODS:Multidisciplinary critical approac...

journal_title：Acta clinica Belgica

authors： Ravelingien T,Buyle F,Deryckere S,Sermijn E,Debrauwere M,Verplancke K,Callens S,Commeyne S,Pattyn C,Vogelaers D

更新日期：2016-10-01 00:00:00

abstract：:Intradural spinal arachnoid cysts are a relatively uncommon lesion that may be either intra, or extradural, and intradural spinal arachnoid cysts are even less common. Arachnoid cysts are cerebrospinal fluid collections in the spine that can present with neurological symptoms. The objective of this paper is to describ...

journal_title：Acta clinica Belgica

authors： Krstačić A,Krstačić G,Butković Soldo S

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:The comprehensive geriatric assessment (CGA) can detect geriatric problems and potentially improve survival, physical, and cognitive state of patients, as well as increase an older person's chances of staying at home longer. In older people, the number and severity of comorbidity increase with age and are an...

journal_title：Acta clinica Belgica

authors： Denewet N,De Breucker S,Luce S,Kennes B,Higuet S,Pepersack T

更新日期：2016-08-01 00:00:00

abstract：:We report and discuss the case of a 51-year-old patient undergoing elective laparoscopic surgery for pheochromocytoma after 10 days of medical pre-treatment. After anaesthetic induction, a deep level of anaesthesia could not prevent the onset of repeated hypertensive peaks, followed by severe hypotensive periods. Once...

journal_title：Acta clinica Belgica

authors： Jakus L,Jacquet LM,Maiter D,Mourad M,Jonas C,Scholtes JL

更新日期：2016-06-01 00:00:00

abstract：:A 12-year-old African girl presented with multiple, sharply bordered hyperpigmented patches predominantly on the dorsal, tip and lateral aspects of the tongue since 1 year (Figs 1 and 2). On clinical examination, we found an obese adolescent girl with a BMI: 26.5 kg/m(2) ( > P97) with acanthosis nigricans of the neck....

journal_title：Acta clinica Belgica

authors： Karine Francine Docx M,Vandenberghe P,Govaert P

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Automated insulin calculators (AICs) with carbohydrate counting (CHC) have been shown to be effective in improving glycated haemoglobin (HbA1c) levels. By contrast, use of AICs without CHC, with predetermined prandial insulin doses modified according to a correction factor and modulated as a function of glyc...

journal_title：Acta clinica Belgica

authors： Oriot P,Ponchon M,Hermans MP

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND/AIM:There are controversial results regarding the relationship of serum 25 hydroxy vitamin D [25(OH)D] and ulcerative colitis (UC) activity. To address this issue, the current study was designed to evaluate the correlation of serum 25(OH)D level and disease activity in patients with UC. METHOD:All consecuti...

journal_title：Acta clinica Belgica

authors： Dolatshahi S,Pishgar E,Jamali R

更新日期：2016-02-01 00:00:00

abstract：:The last two decades have witnessed that flow-assisted analysis of in vitro-activated basophils can constitute a valuable adjunct in the in vitro diagnostic approach of immediate drug hypersensitivity reactions (IDHR). This article summarises the current experience with the basophil activation test in the diagnosis of...

journal_title：Acta clinica Belgica

authors： Mangodt EA,Van Gasse AL,Bastiaensen A,Decuyper II,Uyttebroek A,Faber M,Sabato V,Bridts CH,Hagendorens MM,De Clerck LS,Ebo DG

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Polyarteritis nodosa (PAN) is a rare form of systemic vasculitis, characterized by necrotizing inflammation of medium-sized vessels. In clinical practice, the distinction is made between a limited, mostly cutaneous, form and a generalized form. The Chapel Hill Consensus Conference of 2012 on the classificati...

journal_title：Acta clinica Belgica

authors： Kint N,De Haes P,Blockmans D

更新日期：2016-02-01 00:00:00

abstract：:The authors reported a 56-year-old man with progressive pain over left bottom of oral cavity involving tongue for 3 days. He had a puncture history of tongue by fishbone, which was immediately removed 3 weeks ago. The subsequent contrast-enhanced computed tomography scan of neck disclosed an abscess formation with a f...

journal_title：Acta clinica Belgica

authors： Chen PL,Chiang CW,Shiao CC

更新日期：2015-12-01 00:00:00

abstract：:We describe a case of acquired hepatocerebral degeneration (AHD) presenting with confusion and worsening memory problems since her discharge from the gastroenterology units. Cases of AHD are rare and are frequently confused with hepatic encephalopathy and Wilson's disease. There are no proven pharmacological therapies...

journal_title：Acta clinica Belgica

authors： Ghys C,Kong MF,Glibert G,Lasser L,Karmali R

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:This study aims to evaluate the clinical outcome of fibrinolytic treatment of prosthetic valve thrombosis (PVT) with 'streptokinase' as a first line treatment for these cases. METHODS:The study group was 20 consecutive patients (10 females) diagnosed with PVT. The protocol for streptokinase administration w...

journal_title：Acta clinica Belgica

authors： Sakr SA,Abdel-Shakour H,Ramadan MM

更新日期：2015-06-01 00:00:00

abstract：:Although post-transplant lymphoproliferative disorder is a classical complication encountered after kidney transplantation, its diagnosis can still be challenging and its outcome life-threatening. Most cases are related to Epstein-Barr virus (EBV) infection and occur mainly in the first year post-transplant, favoured ...

journal_title：Acta clinica Belgica

authors： Biller P,Michaux L,Pauw LD,Camboni A,Mourad M,Kanaan N

更新日期：2015-06-01 00:00:00

abstract：:Papillary thyroid cancer is the most common form of thyroid malignancy in children and adult with frequent metastases to the cervical lymph nodes. We present a case of metastatic papillary thyroid cancer with remarkable imaging findings of consecutive metastatic calcified lymph nodes resembling a chain of rings. While...

journal_title：Acta clinica Belgica

authors： Juan YH,Hsuan HF,Ng KK,Ng SH,Yu CW,Liu H,Lin YC

更新日期：2015-04-01 00:00:00

abstract：:We report a rare case of fulminant congestive heart failure with fatal outcome in a 21-year-old girl with systemic lupus erythematosus (SLE). A young woman was admitted in the intensive care unit for pericardial tamponade associated with disseminated coagulopathy and refractory shock secondary to multiple coronary ane...

journal_title：Acta clinica Belgica

authors： Ha Vu N,Duttmann R,De Bels D,Devriendt J,Reper P

更新日期：2014-12-01 00:00:00

abstract：:Hypothyroidism is an endocrine disease with various clinical manifestations. It is a rare cause for rhabdomyolysis and massive pericardial effusion. We describe a case of severe hypothyroidism secondary to autoimmune hashimoto thyroiditis with massive pericardial effusion and rhabdomyolysis. Improvement of mentioned c...

journal_title：Acta clinica Belgica

authors： Zare-Khormizi MR,Rahmanian M,Pourrajab F,Akbarnia S

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE AND IMPORTANCE:Postprandial reactive hypoglycaemia (PRH) is a clinical syndrome characterized by the recurrence of symptomatic hypoglycaemia during postprandial periods. PRH remains a diagnostic challenge for clinicians, because of its atypical manifestations and low prevalence, especially in older persons. ...

journal_title：Acta clinica Belgica

authors： Deliens C,Losseau C,Vandeleene B,Boland B

更新日期：2014-08-01 00:00:00

abstract：:Reversible lesions of the splenium of the corpus callosum constitute a clinicoradiological syndrome that has been associated to various medical conditions. We report the case of a 47-year-old man who presented with encephalopathy associated to auto-immune thyroid disease in which a reversible splenial lesion was isola...

journal_title：Acta clinica Belgica

authors： De Greef J,Jaumotte C,Quivron B,Derue G

更新日期：2014-06-01 00:00:00

abstract：:Since the era of highly active antiretroviral therapy (HAART), HIV is considered a chronic disease. Adherence to HAART is crucial for effectiveness. Non-adherence negatively impacts patient outcome and the larger economy. However, data on adherence among the Belgian HIV cohort are scarce. Therefore, the purpose of thi...

journal_title：Acta clinica Belgica

authors： Degroote S,Vogelaers D,Vermeir P,Mariman A,De Rick A,Van Der Gucht B,Pelgrom J,Van Wanzeele F,Verhofstede C,Vancauwenberghe J,Vandijck D

更新日期：2014-04-01 00:00:00

abstract：:We present the case of a 51-year-old woman who presented a right supraclavicular mass corresponding to lymphadenitis with atypical mycobacterium (Mycobacterium genavense). Later, she developed subcutaneous purulent small nodules containing the same germ. The presence of this mycobacterium was in the context of recurre...

journal_title：Acta clinica Belgica

authors： Numbi N,Demeure F,Van Bleyenbergh P,De Visscher N

更新日期：2014-04-01 00:00:00

abstract：:Azole antifungals are a group of fungistatic agents that can be administered orally or parenterally. The determination of the concentrations of these antifungals (miconazole, fluconazole, ketoconazole, posaconazole, voriconazole, itraconazole, and its major active metabolite, hydroxy-itraconazole) in serum can be usef...

journal_title：Acta clinica Belgica

authors： Mistretta V,Dubois N,Denooz R,Charlier C

更新日期：2014-01-01 00:00:00

abstract：:Psoriasis affects about 2 to 3% of the caucasian population. It is a chronic inflammatory disease affecting predominantly the skin with the involvement of autoimmune mediated mechanisms. Typical pathogenic features include an increased renewal of epidermal keratinocytes, the enlargement of the germinating compartment,...

journal_title：Acta clinica Belgica

authors： de la Brassinne M,Failla V,Nikkels A

更新日期：2013-11-01 00:00:00

abstract：:Insertion sequences IS481 and IS1001 are targets for molecular detection of respectively Bordetella pertussis and Bordetella parapertussis. There is a raising concern about specificity of these targets due to sequence similarity with Bordetella holmesii and Bordetella bronchiseptica. The likelihood of false (para)pert...

journal_title：Acta clinica Belgica

authors： Van den Bossche D,De Bel A,De Smet D,Heylen O,Vekens E,Vandoorslaer K,Soetens O,Piérard D

更新日期：2013-09-01 00:00:00

abstract：:The availability of antiretroviral therapy (ART) has significantly improved the quality of life of persons with HIV infection. However, new problems have arisen as a consequence of this treatment. An immune reconstitution inflammatory syndrome (IRIS) in which patients experience a paradoxical worsening of their clinic...

journal_title：Acta clinica Belgica

authors： Huis in 't Veld D,Lukande R,Lammens M,Conesa-Botella A,Vlieghe E,Van Marck E,Pauwels P,Colebunders R

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:Hospital Acquired Infections (HAIs) are considered to be one of the most serious patient safety issues in healthcare today. It has been shown that HAIs contribute significantly not only to morbidity and mortality, but also to excessive costs for the health care system and for hospitalized patients. Since p...

journal_title：Acta clinica Belgica

authors： Trybou J,Spaepen E,Vermeulen B,Porrez L,Annemans L

更新日期：2013-05-01 00:00:00

abstract：:Urinary schistosomiasis, caused by Schistosoma haematobium, is a prevalent parasitic infection in certain areas of Africa and the Middle East. Humans can be infected by cercariae when they are in contact with contaminated freshwater. The adult worms reside in the veins of the vesical and pelvis plexuses. The urinary b...

journal_title：Acta clinica Belgica

authors： Oyaert M,Lagrange W,Smet G,De Feyter K,Laffut W

更新日期：2013-05-01 00:00:00

abstract：:Calciphylaxis, or calcific uremic arteriolopathy (CUA) is a rare but well described entity in patients with endstage renal disease (ESRD) and/or hyperparathyroidism. CUA is characterized by systemic acute calcification of the small and intermediate dermal vasculature that can lead to epidermal ischemia, ulceration, an...

journal_title：Acta clinica Belgica

authors： Sermijn E,Strobbe T,Vandekerckhove L,Libbrecht L,Colle I,Schoonjans R,Vogelaers D

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Altered iron metabolism plays a central role in the development of anaemia in critically ill patients but the time course of iron status in septic and non-septic critically ill patients has not been well defined. METHODS:Prospective study in a 34-bed medico-surgical ICU. The complete blood count, iron, ferr...

journal_title：Acta clinica Belgica

authors： Piagnerelli M,Cotton F,Herpain A,Rapotec A,Chatti R,Gulbis B,Vincent JL

更新日期：2013-01-01 00:00:00

abstract：:Recurrent abdominal pain may be enigmatic to solve. We report three cases, presenting after a protracted history of severe recurrent bouts of epigastric pain, impeding daily activities. In all cases, serology for strongyloidiasis stercoralis proved positive. In one case, stool examination was positive for larvae. Trea...

journal_title：Acta clinica Belgica

authors： Isen C,Ivens C,Callens SF,Meeuwissen J,Vonck A,Koch A,Vogelaers D

更新日期：2013-01-01 00:00:00

abstract：:Parasitic infestations of the galdbladder and biliary tract are quite rare. Taenia saginata is an intestinal helmint and patients harbouring adult T.saginata tapeworms are mostly asymptomatic and discharge only fecal proglottids. In some cases there might be nonspecific symptoms like vomiting, nausea, epigastric pain,...

journal_title：Acta clinica Belgica

authors： Uygur-Bayramiçli O,Ak O,Dabak R,Demirhan G,Ozer S

更新日期：2012-11-01 00:00:00

abstract：:In Belgium, individual laboratory and treatment data of all HIV-infected patients seen in the 9 AIDS Reference Centres and 7 AIDS Reference Laboratories are collected prospectively since 2006. We present here an analysis of patients recorded in the cohort database between 1st of January 2006 and 31st of December 2008....

journal_title：Acta clinica Belgica

authors： Van Beckhoven D,Buvé A,Ruelle J,Seyler L,Sasse A,Belgian HIV Cohort Study Group.

更新日期：2012-09-01 00:00:00

abstract：:The diffuse infiltration by plasma cells in the liver is not uncommon in multiple myeloma (MM). However, a MM with hepatic mass is very unusual. We report a case of a 75-year-old male with hepatomegaly and a lesion occupying a voluminous space in the liver. A lambda light chain multiple myeloma was found in the check-...

journal_title：Acta clinica Belgica

authors： de Vos M,Druez P,Nicaise M,Ngendahayo P,Sinapi I,Mineur P

更新日期：2012-09-01 00:00:00

abstract：:Gestational diabetes (GDM) is a frequent medical condition during pregnancy. GDM is associated with an increased risk of complications for both the mother and the baby during pregnancy and birth. Women with GDM also have an increased risk of developing type 2 diabetes later in life. Two large randomised intervention t...

journal_title：Acta clinica Belgica

authors： Benhalima K,Van Crombrugge P,Hanssens M,Devlieger R,Verhaeghe J,Mathieu C

更新日期：2012-07-01 00:00:00